Two experiments were performed to examine specificity, integration and differentiation in heart rate (HR) and plethysmographic blood volume pulse amplitude (Pleth. amplitude). In Experiment I it was possible to control two closely related autonomic responses separately under Feedback condition. This specificity was not observed under Non-Feedback condition. Simultaneous feedback of both HR and Pleth. produced greater effects than feedback of the individual responses. Furthermore a Teaming process of voluntary control was examined. In Experiment II the subjects could learn differentiation. Integration was learned more easily than was differentiation. The interaction among responses was discussed.