Exploring
the Relationship Between Having Control and Losing Control to Functional
Neuroanatomy within the Sleeping State
D.H. Shapiro, Jr., J. Wu, C. Hong, M. Buchsbaum, L. Gottschalk, V.E. Thompson, D. Hillyard, M. Hetu & G. Friedmam |
Twelve
normal male subjects were injected with 18 F D-deoxyglucose during
either rapid eye movement (REM) (N = 7) or non-rapid eye movement
(NREM) (N = 5) sleep, When subsequently awakened they reported their
dreams and mentation, which were taperecorded, transcribed, and then
coded along dimensions of perceived control. Non-parametric correlations
between these verbal reports and localized cerebral glucose metabolic
rates obtained from Positron Emission Tomography (PET) scores revealed
significant positive and negative correlations throughout the brain.
Having control was positively associated with activation of frontal
cortex components and negatively correlated with limbic system activation.
Showing internal consistency, there was a significant positive correlation
between loss of control and limbic system activation, and a significant
negative correlation between loss of control and the frontal cortex
(right). Potential implications and importance of these findings
for the study of control and state specific consciousness, clinical
problems such as depression, brain lateralization, and further PET
studies are discussed.
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