Abstract
Effects of hippocampal electrical stimulation on memory consolidation
T. Hirano
Three experiments were conducted to test whether an electrical stimulation of the hippocampus had any effect on memory consolidation. Cats were trained in shuttle-box avoidance in Experiment 1, figural discrimination in Experiment 2, and delayed reaction in Experiment 3. The results revealed that a limbic seizure produced Z min after a trial had no effect on the memory consolidation (in Experiment 1 and 2), No difference was found between subjects with seizure and those without seizure in the number of trials needed to master the problem in both cases when a treatment was administered 1 min after a trial. On the other hand, serious retardation was caused by a hippocampal localized seizure with a minimum duration when it was given immediately after taking away the cue stimulus in the delayed reaction (Experiment 3).